New Cancer Research

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Sent on Tuesday, 2008 Jul 22.

Search candidiasis
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==================== Entrez pubmed Results ======================

Items 1 - 3 of 3

1: Infection. 2008 Jul 19; [Epub ahead of print]

Aspergillus to Zygomycetes: Causes, Risk Factors, Prevention, and Treatment of
Invasive Fungal Infections.

Cornely OA.

Klinik I fur Innere Medizin, Klinikum der Universitat zu Koln, 50924, Cologne,
Germany, oliver.cornely@ctuc.de.

Invasive fungal infections (IFIs) are an important cause of morbidity and
mortality, particularly in patients with underlying risk factors (e.g.,
neutropenia, cancer chemotherapy, transplantation, AIDS). Although Candida
species remain a relevant cause of IFI, other organisms (particularly moulds)
have become increasingly prevalent. In particular, Aspergillus species are the
leading cause of mould infections although other moulds including Fusarium
species and Zygomycetes are increasing in frequency, and are associated with a
high mortality rate. Options available for the prevention and treatment of these
infections include standard and liposomal formulations of amphotericin B, but
toxicity concerns limit their use; fluconazole is effective for the prevention
and treatment of candidiasis but its inactivity against moulds and increasing
resistance are limiting factors. Newer azoles, particularly voriconazole and
posaconazole, have an enhanced spectrum of activity that includes Candida
species, Aspergillus species, Cryptococcus species, dimorphic fungi, Fusarium
species, and, for posaconazole, Zygomycetes. Recent data suggest that these
agents are highly effective in a variety of clinical settings. Echinocandins
have good activity against Candida species and Aspergillus species but their
spectrum generally does not include Fusarium species, Cryptococcus species,
Trichosporon species, Zygomycetes, and dematiaceous moulds. While these agents
are unlikely to exhibit cross-resistance with polyenes or azoles, they must be
administered intravenously. Knowledge of the pathogenesis of IFIs and the
activity, efficacy, and limitations of available treatment options will allow
the selection of an appropriate antifungal agent for individual patients.

PMID: 18642109 [PubMed - as supplied by publisher]

2: J Adv Nurs. 2008 Jul;63(2):146-7.

Interventions for preventing oral candidiasis for patients with cancer receiving
treatment.

Munn Z.

Joanna Briggs Institute, Adelaide, South Australia.

PMID: 18638158 [PubMed - in process]

3: Otolaryngol Pol. 2008;62(2):145-8.

[HIV infected child in otolaryngological practice]

[Article in Polish]

Smiatacz T, Narozny W, Kuczkowski J, Trocha H, Stankiewicz C.

Klinika Chorob Zakaznych AM w Gdansku.

The authors present material about 12 HIV infected children at the age between 0
and 18 years observed and treated in Department of Infectious Diseases Medical
University of Gdansk in the period between 1991 till 2006. Retrospectively
medical records of 4 of them currently undergoing observation and treatment have
been analyzed taking into consideration: ways of HIV infection, applying the
possible retroviral profilactic to a mother and a child, the damaging o of
immunological condition in the period of observation and treatment as well as
the possible head and neck changes. The authors come to conclusion that changes
in oral cavity may be the first symptom of child HIV infection and in the oral
candidiasis symptoms the possibility of HIV infection should be taken into
account.

Publication Types:
English Abstract

PMID: 18637437 [PubMed - in process]